News Express: UM scholar gives talk on how iron affects anti-cancer effects of vitamin C
新聞快訊：澳大學人分享鐵元素對維生素C抗癌影響
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陳修平
Chen Xiuping
澳大學人分享鐵元素對維生素C抗癌影響
澳門大學今（14）日於大學展館演講廳舉行“澳大學人研究講壇”第11講，由澳大中華醫藥研究院教授陳修平以“鐵：維生素C抗腫瘤的搗蛋鬼”為題分享其研究成果，現場座無虛席，也有不少中學師生透過視像在線參與。
講壇上，陳修平指出，醫藥研究界對維生素C寄予了天然無毒抗癌藥物之厚望，因為它具有良好的抗癌作用和低微的毒副作用，同時維生素C有助吸收鐵元素。鐵是人體必須的微量元素，而且最近有研究發現，鐵元素可介導一種新的抗癌策略――鐵死亡。然而，陳修平的研究團隊發現，鐵元素竟然會干擾和逆轉維生素C的抗癌作用。陳修平詳細講解了鐵元素這個“搗蛋鬼”如何影響維生素C抗癌，及其為抗癌研究帶來的挑戰。在問答環節，與會者積極提問，交流氣氛熱烈。
陳修平於2007年獲得北京協和醫學院—清華大學醫學部博士學位，於2008年加入澳大中華醫藥研究院。他長期從事藥理學研究，致力於抗癌、抗炎和心腦血管保護的新藥研發，發表SCI期刊論文150餘篇。
澳大近年來在研究創新方面取得了顯著成效，澳大研究服務及知識轉移辦公室因而組織開展“澳大學人研究講壇”，邀請傑出的澳大學人以通俗易懂的方式介紹其前沿研究成果，通過學術研究創造新知識，引導大眾和青年學生了解研究創新的社會意義和價值，以及與日常生活密切關聯的應用性，提升科學素養。
欲瀏覽官網版可登入以下連結:
https://www.um.edu.mo/zh-hant/news-and-press-releases/presss-release/detail/55286/
UM scholar gives talk on how iron affects anti-cancer effects of vitamin C
The University of Macau (UM) today (14 March) held a talk titled ‘Iron: The Troublemaker of Vitamin C in Cancer Therapy’ as the 11th talk of the UM Scholar Research Forum. Chen Xiuping, professor in the Institute of Chinese Medical Sciences, was the speaker. The talk attracted many UM faculty members and students, as well as teachers and students from secondary schools who joined the event through the internet. According to Prof Chen, vitamin C is a natural and promising anti-cancer drug as it has few toxic and side effects. It helps to absorb iron, an essential trace element for humans that was recently found to induce non-apoptotic cell death—ferroptosis, which is also considered a new anti-cancer strategy. However, his research team found that iron can significantly interfere with and reverse the anti-cancer effect of vitamin C. During the talk, Prof Chen discussed how iron becomes the troublemaker of vitamin C’s anti-cancer effect and the challenges it brings to anti-cancer research.
To read the news on UM’s official website, please visit the following link:
https://www.um.edu.mo/news-and-press-releases/press-release/detail/55286/