News Express: UM honorary doctor Dennis Lo Yuk Ming to give talk on prenatal and cancer liquid biopsies
新聞快訊：澳大榮譽博士盧煜明將談產前和癌症液體活檢
盧煜明將談產前和癌症的液體活檢
Dennis Lo Yuk Ming will give a talk on prenatal and cancer liquid biopsies
澳大榮譽博士盧煜明將談產前和癌症液體活檢
澳門大學將於12月19日（星期二）舉辦榮譽博士講座，邀請被譽為“無創產前檢查之父”的國際著名分子生物學學者盧煜明以“向產前和癌症的液體活檢前沿推進”為題發表演說。歡迎有興趣人士報名參加。
盧煜明現為香港中文大學醫學院副院長（研究），同時兼任李家誠健康科學研究所所長、李家誠醫學講座教授及化學病理學講座教授，重點研究集中於血漿內游離DNA的生物學及診斷應用。他於1997年發現了孕婦血漿中含有高濃度的胎兒DNA，並研發出一套排除因穿刺羊膜檢查而導致高風險的新技術，用於準確分析和量度母親血漿中的胎兒DNA，為孕婦提供了一套安全高效的產前檢測方法。這項無創產檢技術迅速被超過90個國家的實驗室應用作常規檢查，令盧煜明及其研究團隊在非創傷性產前診斷領域上處於世界領先地位。
盧煜明及其研究團隊透過大型平行測序技術及創新的生物信息科技，分析母體血漿中的微量DNA，成功破譯了胎兒的全基因組圖譜，從而及早預測多種遺傳病，其後拓展至癌症篩查，以及監察器官移植排斥等，免卻入侵病人身體抽取活組織的風險。他的研究成果對全球醫學及科學界影響深遠，屢獲國際殊榮，並被選為英國皇家學會院士、美國國家科學院外籍院士及世界科學院院士。
講座上，盧煜明將講解如何以血漿解開身體密碼，探討利用遊離DNA進行液體活檢的產前篩檢和癌症檢測的最新發展，當前困難和未來方向，以改變世界的液體活檢技術的鑰匙為觀眾打開表觀遺傳檢測之門。
講座將於12月19日（星期二）上午10時以英語於澳大聚賢樓地面層多功能廳（N1-G014）舉行。有興趣人士可於以下網址報名：https://umac.au1.qualtrics.com/jfe/form/SV_6gSvyzSAuWlhoJ8。查詢請致電8822 4892或電郵至um_fhs@um.edu.mo。
欲瀏覽官網版可登入以下連結:
https://www.um.edu.mo/zh-hant/news-and-press-releases/press-release/detail/57382/
UM honorary doctor Dennis Lo Yuk Ming to give talk on prenatal and cancer liquid biopsies
The University of Macau (UM) will hold a Doctor honoris causa Lecture on Tuesday 19 December. Dennis Lo Yuk Ming, a world-renowned scholar in molecular biology who is also known as the ‘father of non-invasive prenatal testing’, will give a talk titled ‘Pushing Forward the Frontiers of Prenatal and Cancer Liquid Biopsies’. All are welcome to attend.
Prof Lo is currently the associate dean (research) of the Faculty of Medicine at the Chinese University of Hong Kong (CUHK), the director of the Li Ka Shing Institute of Health Sciences, a Li Ka Shing Professor of Medicine, as well as a chair professor of chemical pathology at CUHK. His research interests focus on the biology and diagnostic applications of cell-free DNA in plasma. In 1997, Prof Lo discovered the high concentration of foetal DNA in maternal plasma. This discovery led him to develop a new technique which can eliminate the high risk associated with amniocentesis and provide safe and effective prenatal testing for the accurate analysis and measurement of foetal DNA in maternal plasma. This non-invasive method has been quickly adopted by laboratories in more than 90 countries as routine testing for pregnant women, placing Prof Lo and his research team at the forefront of non-invasive prenatal diagnosis.
By analysing traces of foetal DNA in maternal plasma with the use of massively parallel sequencing and innovative bioinformatics technologies, Prof Lo and his research team successfully decoded a foetal genome map for the early detection of multiple genetic diseases. The relevant technique can eliminate the risk associated with invasive biopsies and was then further applied to cancer screening and organ transplant rejection monitoring. Prof Lo’s research has had a profound influence on the global medical and scientific community and earned him numerous international honours. He has been elected as a fellow of the Royal Society, a foreign associate of the US National Academy of Sciences, and a fellow of the World Academy of Sciences.
During the talk, Prof Lo will explain how to unveil the body’s secrets with plasma and discuss the latest developments, current challenges, and future directions in prenatal testing and cancer screening using cell-free DNA liquid biopsies, presenting the audience with new insights into liquid biopsy, a world-changing technology.
The talk will begin at 10:00am in the Multi-function Hall of the UM Guest House (N1-G014) and will be conducted in English. Interested individuals can register at https://umac.au1.qualtrics.com/jfe/form/SV_6gSvyzSAuWlhoJ8. For enquiries, please call 8822 4892 or email um_fhs@um.edu.mo.
To read the news on UM’s official website, please visit the following link:
https://www.um.edu.mo/news-and-press-releases/press-release/detail/57382/