News Express: Research paper by State Key Laboratory of Quality Research in Chinese Medicine published in prestigious journal
新聞快訊：中藥質量研究國家重點實驗室論文於權威期刊刊登
中藥質量研究國家重點實驗室論文於《中國科學：生命科學》刊登
A research paper by SKL-QRCM is published in SCIENTIA SINICA Vitae
中藥質量研究國家重點實驗室論文於權威期刊刊登
由中藥質量研究國家重點實驗室團隊撰寫的《基於作用機制的中藥質量研究體系》論文發表於權威期刊《中國科學：生命科學》。該期刊由中國科學院主管、中國科學院與國家自然科學基金委員會主辦。
中藥質量歷來是中藥研究的重點和行業關注的焦點。然而，由於作用機制不明、來源多樣、成分複雜，中藥質量如何更直接體現臨床應用的有效性與安全性，仍然是阻礙中藥產業高質量發展的關鍵科學問題。2020年，中國科學技術協會發佈的十個前沿科學問題中，“調節人體免疫功能的中醫藥機制是什麼”為唯一中醫藥領域的重大科學問題，凸顯了中醫藥機制研究的重要性。
中藥發揮作用的物質基礎及其生物學機制貫穿於中藥研發、生產以及臨床應用活動的全過程，是中藥質量的核心要素。實驗室團隊圍繞中藥質量研究的現狀進行深入分析，提出基於作用機制的中藥質量研究，打通了中藥產業鏈各個環節的底層邏輯，也凸顯了中藥臨床價值的重要科學依據。通過基於藥效機制的中藥有效性評價、基於毒理機制的中藥安全性評價、基於新技術新方法的中藥質量評價、基於質量研究的中藥研發轉化等方向進行有組織的科學研究，將為中藥質量保障輸出原創性標誌物、新技術和新方法，從而促進中藥現代化、國際化和中藥產業高質量發展。
在2024年，澳門大學及澳門科技大學的中藥質量研究國家重點實驗室以重組為契機，進一步明確定位、凝練優勢、加強統籌創新，明確聚焦基於中藥作用機制的質量研究，開展系統深入、有組織的科研活動。該論文是澳大與澳科大實驗室科研人員對實驗室十多年來科學實踐的理論總結，也是對實驗室未來發展方向的展望，其發表將有助於推動中藥質量研究的模式創新和理念創新，彰顯了澳門科學家在推動中醫藥高質量發展的方向性與戰略性的理論貢獻。
欲瀏覽官網版可登入以下連結:
https://www.um.edu.mo/zh-hant/news-and-press-releases/campus-news/detail/60137/
Research paper by State Key Laboratory of Quality Research in Chinese Medicine published in prestigious journal
The paper titled ‘Mechanism-oriented quality research system for traditional Chinese medicine’, authored by the research team from the State Key Laboratory of Quality Research in Chinese Medicine (SKL-QRCM) of the University of Macau (UM), has been published in SCIENTIA SINICA Vitae, a prestigious journal overseen by the Chinese Academy of Sciences, and co-sponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China.
The quality of Chinese medicine has always been a focus of research and industry attention. However, due to the unclear mechanisms of action, diverse sources and varieties, and complex composition of Chinese medicine, the industry has encountered difficulties in establishing a system to show the relationship between the quality of Chinese medicine and the efficacy and safety of clinical applications, which has hindered the high-quality development of the Chinese medicine industry.
The research teams conducted an in-depth analysis of the current state of quality research of Chinese medicine and proposed a mechanism-oriented approach to quality research of Chinese medicine, which elucidates the underlying logic of various segments of the Chinese medicine industry and highlights the clinical value of Chinese medicine. They also introduced new biomarkers, technologies, and methods for more precise quality control of Chinese medicine, thereby promoting the modernisation, internationalisation, and high-quality development of the Chinese medicine industry. The paper is a theoretical summary of more than a decade of scientific practice by researchers from UM and the Macau University of Science and Technology, and will drive innovation in both models and concepts of quality research of Chinese medicine.
To read the news on UM’s official website, please visit the following link:
https://www.um.edu.mo/news-and-press-releases/campus-news/detail/60137/