News Express: UM scholar’s book on computational pharmaceutics published by John Wiley & Sons
新聞快訊:澳大學者計算藥劑學專著獲約翰威立出版社出版
澳大學者計算藥劑學專著獲約翰威立出版社出版
The book Exploring Computational Pharmaceutics – AI and Modeling in Pharma 4.0, edited by a UM scholar, is published by John Wiley & Sons
澳大學者計算藥劑學專著獲約翰威立出版社出版
澳門大學中華醫藥研究院、中藥質量研究國家重點實驗室、健康科學學院公共衛生及醫藥管理學系副教授歐陽德方主編的計算藥劑學專著第二版《Exploring Computational Pharmaceutics ‐ AI and Modeling in Pharma 4.0》由國際著名出版社約翰威立(John Wiley & Sons, Inc)出版。該書匯聚了全球製藥學術界、工業界和監管部門的頂級專家,總結了過去十年計算藥劑學的變革和前沿進展,並展望Pharma 4.0時代的潛力和發展方向。
當前,製藥科學家們正面臨藥物開發成本高、週期長、成功率低的挑戰。過去十年間,製藥行業的數字化轉型浪潮為提高藥物開發效率帶來了新的機會。自2011年起,歐陽德方先鋒性地將人工智能和多尺度模擬技術用於藥物製劑研究,開創了“計算藥劑學”研究方向。他主編的有關領域第一部專著《Computational Pharmaceutics》於2015年由約翰威立出版,受到廣泛關注和好評。近十年來,計算藥劑學領域迅猛發展並廣泛應用於製藥產業界。為了回應廣大讀者的期待和出版社的熱忱邀請,歐陽德方自2021年起著手編著計算藥劑學系列專著第二版《Exploring Computational Pharmaceutics ‐ AI and Modeling in Pharma 4.0》,歷時三年出版。
該書內容涉及人工智能、分子模擬、過程模擬、智能製造、定量藥理學等廣泛主題,以多尺度視角揭示了配方前研究、配方工藝研究、臨床研究,以及精準醫療中的物理、化學和數據驅動的關鍵。各章還具體介紹了前沿計算技術在傳統劑型和高級藥物遞送系統中的應用。目標讀者群體包括製藥科學家、計算化學家和計算機科學家,藥物化學家、臨床藥師、材料科學家也可以從中獲益,並可激勵更多學者投入到計算藥劑學這一重要研究領域,對計算藥劑學的發展將產生重要貢獻。詳情:https://onlinelibrary.wiley.com/doi/book/10.1002/9781119987260。
歐陽德方具有藥劑學和計算機的跨科學背景,並在製藥工業界和學術界擁有豐富經驗。他的研究方向為計算藥劑學,並在該領域發表高水平SCI論文100餘篇。他於2010年在澳大利亞昆士蘭大學藥學院獲博士學位,博士論文獲院長獎。2011年1月起,他在英國阿斯頓大學藥學系任藥劑學講師;2014年11月加入澳大中華醫藥研究院任教。
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https://www.um.edu.mo/zh-hant/news-and-press-releases/presss-release/detail/58619/
UM scholar’s book on computational pharmaceutics published by John Wiley & Sons
The book Exploring Computational Pharmaceutics – AI and Modeling in Pharma 4.0, edited by Ouyang Defang, associate professor at the Institute of Chinese Medical Sciences, the State Key Laboratory of Quality Research in Chinese Medicine, and the Department of Public Health and Medicinal Administration of the Faculty of Health Sciences at the University of Macau (UM), has been published by John Wiley & Sons, Inc. The book is the second edition of Computational Pharmaceutics. Bringing together leading pharmaceutical experts from academia, industry, and regulatory agencies, the book provides an overview of the changes and advances made in computational pharmaceutics over the past decade and explores the potential and future outlook of the Pharma 4.0 era.
Pharmaceutical scientists are currently faced with the challenges of high costs, long lead times, and low success rates in drug development. Over the past decade, the wave of digital transformation in the pharmaceutical industry has presented new opportunities to improve the efficiency of drug development. Since 2011, Prof Ouyang has pioneered the integration of artificial intelligence and multi-scale modelling in pharmaceutical research, creating a new research field of ‘computational pharmaceutics’. He edited the first monograph in the field, Computational Pharmaceutics, which was published by John Wiley & Sons in 2015 and received wide attention and positive feedback. Over the past decade, the field of computational pharmaceutics has developed rapidly and has been widely applied in the pharmaceutical industry. In response to readers’ expectations and the publisher’s invitation, Prof Ouyang started working on the second edition of Computational Pharmaceutics, Exploring Computational Pharmaceutics ‐ AI and Modeling in Pharma 4.0, in 2021, and the book was successfully published after three years.
The book covers a wide range of topics including artificial intelligence, molecular modelling, process simulation, intelligent manufacturing, and quantitative pharmacology. It provides a multi-scale perspective that reveals the physical, chemical and data-driven details of pre-formulation studies, formulation, process, clinical studies, and precision medicine. The chapters also provide specific information on the application of cutting-edge computational technologies in both conventional dosage forms and advanced drug delivery systems. The book is aimed at pharmacologists, computational chemists, and computer scientists. It will also benefit pharmaceutical chemists, clinical pharmacists and materials scientists, and encourage more researchers to engage in the field of computational pharmaceutics, thereby making a significant contribution to the pharmaceutical industry. For publication details, please visit: https://onlinelibrary.wiley.com/doi/book/10.1002/9781119987260.
Prof Ouyang has an interdisciplinary background in pharmacy and computer science, with extensive experience in both the pharmaceutical industry and academia. His research interest is in computational pharmaceutics and he has published over 100 SCI journal papers in the field. Prof Ouyang received his PhD degree from the School of Pharmacy at the University of Queensland, Australia, in 2010, and was awarded the Dean’s Award for his PhD thesis. He has been a lecturer in pharmaceutics at Aston University, UK, since January 2011, and joined the Institute of Chinese Medical Sciences at UM in November 2014.
To read the news on UM’s official website, please visit the following link:
https://www.um.edu.mo/news-and-press-releases/press-release/detail/58619/