News Express: UM scholar shares new development model of TCM innovation
新聞快訊：澳大學人分享創新中藥發展新模式
林理根
Lin Ligen
澳大學人分享創新中藥發展新模式
澳門大學今（24）日舉行“澳大學人研究講壇”第32講，由澳大中華醫藥研究院、中藥機制與質量全國重點實驗室教授、健康科學學院藥物科學系副系主任林理根以“中藥化學生物學——創新中藥發展新模式”為題發表演說。講座吸引一眾師生及公眾參與，現場討論氣氛熱烈。
講座中，林理根介紹了中藥化學生物學這一前沿學科，並闡述其如何推動中藥現代化與創新研發。他解釋，該學科融合中藥化學、分子生物學、系統生物學等方法，從化學成分與生物系統的互動中解析中藥的作用原理；其核心是以中藥化學成分作為分子探針，揭示生命過程的調控機制，同時以生物效應為導向發現和創新藥物。林理根也分享了其團隊在中藥材楊梅與野菊花方面的研究成果，展示了中藥化學生物學在創新中藥開發上的實際應用。
林理根的研究聚焦代謝性疾病（如肥胖與糖尿病）的分子機制，並致力從中藥與天然產物中篩選活性小分子；其研究共獲得18項資助，包括國家自然科學基金、澳門科學技術發展基金、粵港澳聯合項目等。迄今為止，林教授作為通訊作者或第一作者於SCI期刊發表130多篇論文，並自2020年起連續入選全球前2%頂尖科學家榜單。此外，他亦於《Chinese Medicine》等學術期刊擔任編委。
“澳大學人研究講壇”由澳大研究服務及知識轉移辦公室舉辦，邀請傑出的澳大學人以通俗易懂的方式介紹其前沿研究成果，讓大眾了解研究創新的社會意義，以及與日常生活密切關聯的應用性。
欲瀏覽官網版可登入以下連結:
https://www.um.edu.mo/zh-hant/news-and-press-releases/press-release/detail/63556/
UM scholar shares new development model of TCM innovation
The University of Macau (UM) held the 32nd UM Scholar Research Forum today (24 March), where Lin Ligen, professor in the Institute of Chinese Medical Sciences and the State Key Laboratory of Mechanism and Quality of Chinese Medicine and associate head of the Department of Pharmaceutical Sciences in the Faculty of Health Sciences at UM, delivered a talk titled ‘Traditional Chinese Medicine (TCM) Chemical Biology: A New Developing Model for TCM Innovation’. The talk was well attended by students, faculty, and members of the public.
During the talk, Prof Lin discussed the role of traditional Chinese medicine chemical biology in driving the modernisation, innovation, and research and development of TCM. He explained that this interdisciplinary field integrates methodologies from Chinese medicine chemistry, molecular biology, systems biology, and other areas, and aims to elucidate the mechanisms of TCM action by examining the interaction between chemical components and biological systems. Prof Lin also presented his research team’s findings on Chinese bayberry and wild chrysanthemum, and showcased the practical application of traditional Chinese medicine chemical biology in TCM development.
To read the news on UM’s official website, please visit the following link:
https://www.um.edu.mo/news-and-press-releases/press-release/detail/63556/